Read this chapter and begin filling in the outline below before attending the lecture on this material.
Chapter Outline:
I. CELL DIVISION
1. Chromosome Structure -
Eukaryotic Chromosomes = DNA + Proteins
Total number of chromosomes in humans = 46 (23 pairs)
Karyotypes =
2. The Cell's Life Cycle -
Interphase - 90% of the cell's life is spent in interphase
G1, S, G2
4 Stages of MITOSIS - nuclear division
PROPHASE
METAPHASE
ANAPHASE
TELOPHASE
Cytokinesis
Cell Plate
Cleavage Furrow
*Be sure you can identify the stages of mitosis
and interphase - see figure 6.8 in your text
II. CANCER - a growth disorder
of cells caused by uncontrolled cell division
*1 of every 4 deaths in U.S. is caused by cancer
30% of those are deaths from LUNG CANCER
1. Tumor -
2. Sarcoma -
3. Carcinoma -
4. Metastases -
5. Carcinogens -
6. Mutagens -
*in cigarettes, vinyl chloride, benzo pyrenes, nicotine
derivatives
7. Oncogenes - genes which
have the potential to cause cancer (usually genes which are associated
with cell growth)
Life Application: Read
pgs. 548-549, "The Nature of Lung Cancer"
Cancer Treatments -
Surgery, Radiation, Chemotherapy (pgs. 146-147)
III. MEIOSIS -
Sexual Reproduction results in the combination of an egg and sperm which produces genetically unique individuals (23 + 23 = 46) 46 = 2n
HAPLOID =DIPLOID =
The STAGES OF MEIOSIS =
PROPHASE I
METAPHASE I
ANAPHASE I
TELOPHASEPROPHASE II
METAPHASE II
ANAPHASE II
TELOPHASE II
Crossover - occurs between non-sister chromatids of homologous chromosomes; pieces of genetic material are exchanged